Jason Chen Selected Research

PXS25 compound

1/2015

A cationic-independent mannose 6-phosphate receptor inhibitor (PXS64) ameliorates kidney fibrosis by inhibiting activation of transforming growth factor-β1.

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Jason Chen Research Topics

Disease

14	Neoplasms (Cancer) 01/2021 - 01/2007
11	Infections 01/2022 - 04/2009
6	Fibrosis (Cirrhosis) 10/2022 - 01/2015
4	Multiple Myeloma 01/2021 - 05/2017
4	Thrombosis (Thrombus) 01/2021 - 01/2018
3	Albuminuria 10/2022 - 01/2017
3	Obesity 10/2022 - 01/2017
3	Body Weight (Weight, Body) 01/2022 - 01/2013
3	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 12/2020 - 01/2019
3	Chickenpox 08/2017 - 04/2015
3	Herpes Zoster 08/2015 - 01/2012
2	Inflammation (Inflammations) 10/2022 - 01/2022
2	Chronic Renal Insufficiency 10/2022 - 01/2020
2	Hemorrhagic Cystitis 01/2022 - 10/2021
2	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2022 - 11/2021
2	Respiratory Syncytial Virus Infections 02/2021 - 01/2019
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2021 - 12/2018
2	Type 2 Diabetes Mellitus (MODY) 01/2021 - 11/2019
2	Venous Thromboembolism 01/2019 - 01/2017
2	Glioblastoma (Glioblastoma Multiforme) 01/2018 - 03/2016
2	Glioma (Gliomas) 01/2018 - 12/2011
2	Breast Neoplasms (Breast Cancer) 01/2017 - 03/2015
2	Substance-Related Disorders (Drug Abuse) 01/2017 - 11/2014
2	Neoplasm Metastasis (Metastasis) 01/2014 - 12/2011
1	Asthma (Bronchial Asthma) 01/2022
1	Severe Acute Respiratory Syndrome 11/2021
1	Water Intoxication 10/2021
1	Pain (Aches) 01/2021
1	Hypertension (High Blood Pressure) 01/2021
1	Hemophilia A (Haemophilia) 01/2021
1	Eye Diseases (Eye Disease) 01/2021
1	Hyperbilirubinemia 12/2020
1	Viremia 04/2020
1	Lymphoma (Lymphomas) 02/2020
1	Histiocytosis 02/2020

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2015
4	VaccinesIBA 11/2021 - 04/2009
4	CytokinesIBA 02/2021 - 12/2017
3	CreatinineIBA 01/2022 - 01/2016
3	Thrombin FDA Link 01/2021 - 01/2018
3	FibrinIBA 01/2021 - 01/2018
3	Antiviral Agents (Antivirals)IBA 04/2020 - 01/2019
3	CollagenIBA 01/2019 - 01/2015
3	Thromboplastin (Tissue Factor)IBA 01/2019 - 01/2018
3	Biomarkers (Surrogate Marker)IBA 03/2016 - 03/2015
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022 - 10/2021
2	Messenger RNA (mRNA)IBA 01/2022 - 01/2015
2	Mannose (D-Mannose)IBA 01/2022 - 01/2015
2	Pharmaceutical PreparationsIBA 01/2022 - 01/2017
2	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2021
2	cabozantinibIBA 01/2021 - 12/2011
2	Metformin (Glucophage)FDA LinkGeneric 01/2021 - 01/2018
2	Folic Acid (Vitamin M)FDA LinkGeneric 01/2020 - 01/2018
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019 - 06/2017
2	Biological ProductsIBA 06/2018 - 03/2015
2	Temozolomide (Temodar)FDA LinkGeneric 01/2018 - 03/2016
2	Fibronectins (Fibronectin)IBA 01/2018 - 01/2015
2	Gemcitabine FDA Link 12/2017 - 01/2007
2	DNA (Deoxyribonucleic Acid)IBA 03/2016 - 08/2015
2	ParaffinIBA 01/2014 - 09/2012
1	Hydralazine (Apresoline)FDA LinkGeneric 10/2022
1	Urea (Carbamide)FDA LinkGeneric 01/2022
1	Calcineurin InhibitorsIBA 01/2022
1	LipidsIBA 01/2022
1	OvalbuminIBA 01/2022
1	Vancomycin FDA LinkGeneric 01/2022
1	MucinsIBA 01/2022
1	Epoxide HydrolasesIBA 01/2022
1	AerosolsIBA 01/2022
1	Mesna (Coenzyme M)FDA LinkGeneric 10/2021
1	Interleukin-6 (Interleukin 6)IBA 02/2021
1	Interleukin-8 (Interleukin 8)IBA 02/2021
1	Adenine FDA LinkGeneric 01/2021
1	Tricarboxylic AcidsIBA 01/2021
1	Retinaldehyde (Retinal)IBA 01/2021
1	Glutamic Acid (Glutamate)FDA Link 01/2021
1	Biosimilar PharmaceuticalsIBA 01/2021
1	Glutamine (L-Glutamine)FDA Link 01/2021
1	GlutaminaseIBA 01/2021
1	InterleukinsIBA 01/2021
1	Antihypertensive Agents (Antihypertensives)IBA 01/2021
1	Factor XI (Plasma Thromboplastin Antecedent)IBA 01/2021
1	Factor IX (Coagulation Factor IX)FDA LinkGeneric 01/2021
1	Everolimus FDA Link 01/2021
1	EnzymesIBA 01/2021
1	Opioid Analgesics (Opioids)IBA 01/2021
1	Enzyme Precursors (Zymogens)IBA 01/2021
1	Interleukin-33IBA 01/2021
1	Carnitine (L-Carnitine)FDA LinkGeneric 12/2020
1	Transaminases (Aminotransferases)IBA 12/2020
1	Foscarnet FDA LinkGeneric 04/2020
1	Ganciclovir (Cytovene)FDA LinkGeneric 04/2020

Therapy/Procedure

9	Therapeutics 01/2020 - 05/2006
5	Drug Therapy (Chemotherapy) 12/2019 - 04/2015
4	Stem Cell Transplantation 01/2019 - 04/2015
2	Transplantation 01/2022 - 04/2015
2	Gastrectomy 01/2021 - 08/2015
2	Cell Transplantation 04/2020 - 01/2020
1	Homologous Transplantation 10/2021
1	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2021